SKYN® PhD

Cosmeceuticals are products that have both cosmetic and therapeutic (medical or drug-like) effects, and are intended to have a beneficial effect on skin health and beauty. Like cosmetics, they are applied topically as creams or lotions but contain active ingredients that have an effect on skin cell function.

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• Recent progress on biological production of α-arbutin
• Dual functional bioactive-peptide, AIMP1-derived peptide (AdP), for anti-aging

ATX-101 (deoxycholic acid) is the first pharmaceutical therapy approved by the FDA for the reduction in submental fat. Deoxycholic acid is an endogenous secondary bile acid that normally solubilizes dietary fat, contributing to its breakdown and absorption within the gut.

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• The development, evidence, and current use of ATX-101 for the treatment of submental fat

From the Blog

• CoolSculpting vs. Chin Up Double Chin Injections: Doctors Explain the Differences

Dermal fillers are small injections of gel, typically made up of hylauronic acid, that fill in wrinkles and add volume to soft tissue. You can have dermal fillers in different parts of your face: around the eye, cheeks, mouth and jawline, as well as lip fillers administered directly into the lip tissue.

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• Injectables Safety
• Effects of highly concentrated hyaluronic acid filler on nasolabial fold correction- A 24-month extension study
• Remodeling of periorbital, temporal, glabellar, and crow’s feet areas with hyaluronic acid and botulinum toxin
• Clinical comparison between two hyaluronic acid-derived fillers in the treatment of nasolabial folds in Chinese subjects- BioHyalux versus Restylane

From the Blog

• The best aesthetic treatments for all ages from your 20s to 60s

It is believed that as much as 80% of premature ageing of the skin may occurs within the first 20 years of life. Skin biological starts aging at the age of 14-15. At the age of 28-30 the first signs of ageing appear. There are two different types of aging, Intrinsic ageing caused by genes we inherit, which is actually natural skin ageing. The other, caused by environmental factors such as sun exposure, smoking, alcohol, repetitive facial expression and so on, is called Extrinsic ageing and is in reality premature skin ageing.

From the Blog

• The Facial Ageing Process

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• Validation of digital photographic reference scales for evaluating facial aging signs
• Basic analysis of facial ageing- The relationship between the superficial musculoaponeurotic system and age

Laser and light therapies have offered significant advances in dermatological therapy in the past several decades, having evolved significantly from the early use of the ruby laser in 1960 to the current time when such technologies have become a mainstay of treatment for a host of medical and surgical conditions.

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• The ‘Magic Light’- A Discussion on Laser Ethics
• Altshuler_et_al-2001-Lasers_in_Surgery_and_Medicine-1

From the Blog

• The best aesthetic treatments for all ages from your 20s to 60s

Lasers are the standard modality for tattoo removal. Though there are various factors that determine the results, we have divided them into three logical headings, laser dependant factors such as type of laser and beam modifications, tattoo dependent factors like size and depth, colour of pigment and lastly host dependent factors, which includes primarily the presence of a robust immune response. Modifications in the existing techniques may help in better clinical outcome with minimal risk of complications. This article provides an insight into some of these techniques along with a detailed account of the factors involved in tattoo removal.

From the Blog

• The Facts • Laser Tattoo Removal

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• The Kirby-Desai Scale- A Proposed Scale to Assess Tattoo-removal Treatments
• Optimising Laser Tattoo Removal
• Laser tattoo removal- do we already have picosecond lasers_

Lipodissolve injections reduce the size of localized fat deposits and cause skin retraction in body regions containing small deposits of localized fat, cellulite, or postlipoplasty deformities.

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• Lipodissolve for Subcutaneous Fat Reduction and Skin Retraction

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• Resveratrol and its Related Polyphenols Contribute to the Maintenance of Genome Stability

Melasma (also known as chloasma faciei, or the mask of pregnancy when present in pregnant women) is a tan or dark skin discoloration. Melasma is thought to be caused by sun exposure, genetic predisposition, hormone changes, and skin irritation.

From the Blog

• Using Spectra Laser Toning to Manage Melasma
• MELASMA Triggers & Treatments

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• Future therapies in melasma- What lies ahead_
• Early clinical and histological changes induced by microneedling in facial melasma- A pilot study
• DNA Methyltransferases in Malar Melasma and Their Modification by Sunscreen in Combination with 4_ Niacinamide, 0.05_ Retinoic Acid, or Placebo

In society, men with larger penises tend to be viewed as more “powerful” and “masculine,” and this message is propagated in our mainstream media.1,2 As a result, men who perceive their penises to be smaller than average may become concerned that they are less “manly” than their peers.

Although interest in penile augmentation procedures is increasing, there is a significant lack of research into the psychological and psychosexual outcomes of these procedures.

We also investigate Atypical Pearly Penile Papules Mimicking Primary Syphilis.

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• Scrotal Rejuvenation
• Nonsurgical Medical Penile Girth Augmentation- Experience-Based Recommendation
• Nonsurgical Medical Penile Girth Augmentation- A Retrospective Study of Psychological and Psychosexual Outcomes
• Glans Penis Augmentation Using Hyaluronic Acid Gel as an Injectible Filler
• Use of Macrolane VRF 30 in Emicircumferential Penis Enlargement
• The Prevalence of Penile Pearly Papules among Young Men
• The Effects of Penile Girth Enhancement using Injectible Hyaluronic Acid Gel, a Filler
• Laser therapy for the treatment of pearly penile papules
• Co-overexpression of VEGF and GDNF in adipose-derived stem cells optimizes therapeutic effect in neurogenic erectile dysfunction model
• Atypical Pearly Penile Papules Mimicking Primary Syphillis

Platelet-rich plasma (PRP) is an autologous concentration of human platelets in a small volume of plasma. Therefore, the term PRP is preferred to autologous platelet gel, plasma-rich growth factors (PRGFs), or a mere autologous platelet concentrate. Because it is a concentration of platelets, it is also a concentration of the 7 fundamental protein growth factors proved to be actively secreted by platelets to initiate all wound healing.

From the Blog

• THREAD LIFT, FILLERS or PRP. What’s best for you?
• Unexpected Treatments for Firm, Glowing, Flawless Skin
• Everything you Need-to-Know About Platelet Rich Plasma Therapy
• What you need to know about the PRP ‘Vampire Facial’

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• A Patient’s Guide to Natural Healing
• Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss
• The Potential of Topical and Injectable Growth Factors and Cytokines for Skin Rejuvenation
• Platelet-rich plasma, the ultimate secret for youthful skin elixir and hair growth triggering
• Platelet-Rich Plasma Combined with Fractional Laser Therapy for Skin Rejuvenation
• Platelet Rich Plasma evidence to support its use Marx
• Induction of Dermal Collagenesis, Angiogenesis, and Adipogenesis in Human Skin by Injection of Platelet-Rich Fibrin Matrix
• Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment_ Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems
• Autologous platelet-rich plasma versus readymade growth factors in skin rejuvenation- A split face study

Radio-frequency skin tightening is an aesthetic technique that uses radio frequency (RF) energy to heat skin with the purpose of stimulating cutaneous collagen, elastin and hyaluronic acid production in order to reduce the appearance of fine lines and loose skin.

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• What is Radio Frequency Skin Tightening: Overview, Benefits, and Expected Results

From the Blog

• The best aesthetic treatments for all ages from your 20s to 60s

Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance. This aging process is accompanied with phenotypic changes in cutaneous cells as well as structural and functional changes in extracellular matrix components such as collagens and elastin.

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• Validation of digital photographic reference scales for evaluating facial aging signs
• Structural Aging- The Facial Recurve Concept
• New Insights into Skin Appearance and Measurement
• Genetic polymorphisms and skin aging- the identification of population genotypic groups holds potential for personalized treatments
• Basic analysis of facial ageing- The relationship between the superficial musculoaponeurotic system and age
• Aging_in_the_Male_Face__Intrinsic_and_Extrinsic.1

Microneedling is a minimally invasive cosmetic procedure that’s used to treat skin concerns via collagen production. Also known as collagen induction therapy, this treatment may help those looking to reduce the appearance of acne scars and stretch marks.

It’s also used in certain anti-aging procedures, such as eyelid surgery and sun spots.

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• Therapeutic effect of microneedling and autologous plateletrich plasma in the treatment of atrophic scars- A randomized study
• Acne scarring treatment using skin needling

The Silhouette Soft Thread Lift is a treatment which has been praised as the non-surgical replacement for face lifts, avoiding long recovery times, excessive scarring and the use of incisions or sedation. Thread lifts work by placing dissolvable threads under the skin using a fine needle, which elevates sagging tissue, and simultaneously increases collagen production, firming the skins appearance.

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• Outcomes in thread lift for face and neck- A study performed with Silhouette Soft and Promo Happy Lift double needle, innovative and classic techniques

Wrinkle relaxers or “neuromodulators” work by temporarily paralyzing the facial muscles that cause wrinkling. Wrinkle relaxers are injected with a fine needle directly into the muscles. The most common treatment areas include frown lines between the eyebrows and lines around the eyes and mouth.

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• Injectables Safety
• Advances in the use of botulinum neurotoxins in facial esthetics
• Three-Dimensional Evaluation of Static and Dynamic Effects of Botulinum Toxin A on Glabellar Frown Lines
• The efficacy and complications of a new technique of Abobotulinum-toxin A (Dysport) injection in patients with glabellar lines
• Six years of experience using an advanced algorithm for botulinim toxin application
• Real-world effectiveness of onabotulinumtoxinA treatment for the prevention of headaches in adults with chronic migraine in Australia- a retrospective study
• Botulinum toxin drugs- brief history and outlook

From the Blog

• How to Find the Perfect Aesthetic Treatment

Finger on the pulse studies and industry information.

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